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Latin word semel comes from Proto-Indo-European *sem-tio-, Proto-Indo-European *meh₁-lo-, and later Proto-Indo-European *sm̥- (One. With, together.)
*sem-tio- (Proto-Indo-European)
*meh₁-lo- (Proto-Indo-European)
*sm̥- (Proto-Indo-European)
One. With, together.
*sm̥-meh₁lom (Proto-Indo-European)
semel (Latin)
Once, a single time.