
Italian word nipote comes from Proto-Indo-European *nepoder-, Proto-Indo-European *nepot-, and later Proto-Italic *nepōts (Grandson. Nephew.)
*nepoder- (Proto-Indo-European)
*nepot- (Proto-Indo-European)
grandchild, sister's son
*nepōts (Proto-Italic)
Grandson. Nephew.
nepos (Latin)
(figuratively) a spendthrift, prodigal. A descendant. A granddaughter. A grandson. A nephew.
nipote (Italian)
(by extension, in the plural) descendants. Grandchild, grandson, granddaughter. Nephew, niece, nibling.